Ultima-Selank 5mg Ultima Pharma USA

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ACTIVE SUBSTANCE: Selank

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Selank Peptide: Usage, Benefits, Side Effects, and Target Applications

The recent surge in biotechnology has paved the way for the study of novel biologically-active substances, including cognitive enhancers or nootropics.

One such substance is Selank, previously known as TP-7, which falls under the category of synthetic peptides or small artificially-designed proteins.

Selank is often hailed as an anti-anxiety agent, with claims of improving learning and boosting energy levels, purportedly devoid of side-effects or the risk of addiction.

Small in size compared to naturally-occurring proteins, Selank was developed through collaboration between the Institute of Molecular Genetics (Russian Academy of Sciences) and the V.V. Zakusov Research Institute of Pharmacology (Russian Academy of Medical Sciences), alongside its counterpart drug, Semax.

Derived from the combination of tuftsin, a natural peptide found in the body, and another sequence enhancing molecular stability, Selank is designed to reduce anxiety and elevate serotonin levels, with reported slightly higher efficacy compared to tuftsin.

In Russia, Selank has been approved for treating generalized anxiety disorder (GAD) and as a nootropic, although the FDA has not endorsed its use for any conditions. Nevertheless, Selank remains accessible in several countries, often marketed as a dietary supplement.

Mechanism of Action:

While the exact mechanisms of Selank are not fully elucidated, it is believed to stabilize enkephalins in the bloodstream, countering the stress response. However, findings from an animal study in mice did not confirm this stabilization nor significant anti-anxiety effects.

Selank may also bind to GABA receptors, potentially inducing sedative effects. A study on mice reported increased activity in inhibitory neurons, resulting in decreased overall brain activity, indicative of sedation.

Some research suggests Selank's role in increasing brain-derived neurotrophic factor (BDNF), crucial for learning and memory, and modulating neurotransmitter levels like norepinephrine, dopamine, and serotonin, implicated in motivation and pleasure.

Effects:

Selank shows promise in curbing anxiety, with reports of reduced symptoms in clinical trials and animal studies, although further research is warranted.

Memory enhancement and neuroprotection in brain damage have been observed in animal studies, while potential benefits in depression, antioxidant activity, and cardiovascular effects are under investigation.

Safety:

While Selank exhibits diverse potential benefits, caution is advised due to limited human studies and uncertainties regarding long-term safety and efficacy. Always consult a healthcare professional before considering Selank or any other supplement.

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