SELANK 5 Deus Medical

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ACTIVE SUBSTANCE: Selank

1 vial is 5 mg

Selank Peptide: Applications, Benefits, Drawbacks, and Target Indications

Recent development in the field of biotechnology has brought with it an opportunity to research new biologically-active substances like cognitive enhancers or nootropics.

One of these is Selank, previously known as TP-7, that falls under the category of synthetic peptides or short artificially-made proteins.

Selank has been widely touted as an anti-anxiety drug, with its capacity to facilitate learning and boost energy levels, allegedly without side-effects or potential for addiction.

Small in molecular size compared to naturally occurring proteins, Selank was developed by collaborative research between the Institute of Molecular Genetics (Russian Academy of Sciences) and the V.V. Zakusov Research Institute of Pharmacology (Russian Academy of Medical Sciences), alongside its counterpart medication, Semax.

Developed by merging tuftsin, a naturally found peptide in the body, with another molecule that enhances the stability of molecules, Selank is designed to decrease anxiety levels and enhance the amount of serotonin, with some claiming its slightly increased efficiency compared to tuftsin.

In Russia, Selank has been sanctioned for the treatment of generalized anxiety disorder (GAD) and as a nootropic, though the FDA has not approved its use for any condition. However, Selank is still available in a number of countries, frequently sold as a dietary supplement.

Mechanism of Action:

Though the mechanisms of action of Selank are not yet fully understood, it is speculated to stabilize enkephalins in the bloodstream to act against the stress response. In an animal test on mice, however, stabilization or significant anti-anxiety activity was not demonstrated.

Selank is also believed to act by binding to GABA receptors, with sedation effects possibly due to this mechanism. Enhanced activity of inhibitory neurons, with resulting reduced overall brain activity, characteristic of sedation, was observed in mice in one study.

There is some evidence that Selank's action in increasing brain-derived neurotrophic factor (BDNF) involved in learning and memory, and regulating neurotransmitter activity like norepinephrine, dopamine, and serotonin involved in motivation and pleasure.

Effects:

Selank is promising for the blockade of anxiety, with reduced symptomatology being reported in clinical trials and animal studies, but more studies are required.

Memory enhancement and neuroprotection in brain trauma have been observed in animal studies, whereas potential benefits in depression, antioxidant effect, and cardiovascular effects are under investigation.

Safety:

Although Selank shows diverse potential benefits, caution must be exercised due to limited human trials and concerns regarding long-term safety and effectiveness. Always consult a healthcare professional before considering taking Selank or any supplement.

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